The study intends to identify the opportunities of business community integration into ethnic clusters in regional economic space. The following methods were used in the article: monographic, structural and logical analysis. Systematic approach was used as the basis for the research. Its capabilities were supported by the relevant ones of evolutional and institutional economic theories, the theory of socio-economic transformations. The possibilities of ethnic entrepreneurs clustering within the regional economic space were identified: 1) formation of cluster areas of regional economy new growth taking into account the ethnic factor; 2) implementation of ethnic clustering based on a detailed relation of public-private partnership; 3) transformation of priority ethnic clusters into functional subsystems of the regional economy.